Abstract Multiple myeloma (MM) is a heterogeneous disease characterized by frequent MYC translocations.Sporadic MYC activation in the germinal center of genetically engineered Vk*MYC mice is sufficient to induce plasma cell tumors in which a variety of secondary mutations are spontaneously acquired and selected over time.Analysis of 119 Vk*MYC myel
Environmental Alterations
The uneven outcome of decades of fossil fuel extractive economies of growth is clearly visible in the skylines of Indoor Water Fountain cities: indulgence or negligence abound.Louisiana, in the Gulf of Mexico, is one such example.Furthermore, it is subjected to the environmental alteration of the gigantic Mississippi watershed, and on the trajector
Exploring optimal joint operating rules for large-scale inter-basin water transfer projects with multiple water sources, diversion routes, and water demand areas
Study region: The Jiangsu Province section of the South-to-North Water Diversion Project (JS-SNWDP) is an essential section of the SNWDP, which includes multiple water sources, diversion routes, and water demand areas.Study focus: Exploring effective operating rules for the JS-SNWDP is critical to improving its long-term operational performance.How
Increased ratio of dietary carbohydrate to protein shifts the focus of metabolic signaling from skeletal muscle to adipose
Abstract Background The Dietary Reference Intakes PURE BLACK CHERRY (DRI) established acceptable macronutrient distribution ranges (AMDR) for carbohydrates and protein, however little is known about differences in glycemic regulations and metabolic signaling across this range.This study examined metabolic outcomes associated with intake of two diet